Co-controllability of drug-disease-gene network
نویسندگان
چکیده
منابع مشابه
Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets.
The protein-protein interaction (PPI) network is crucial for cellular information processing and decision-making. With suitable inputs, PPI networks drive the cells to diverse functional outcomes such as cell proliferation or cell death. Here, we characterize the structural controllability of a large directed human PPI network comprising 6,339 proteins and 34,813 interactions. This network allo...
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ژورنال
عنوان ژورنال: New Journal of Physics
سال: 2015
ISSN: 1367-2630
DOI: 10.1088/1367-2630/17/8/085009